Title of article :
Pneumothorax and Acute Kidney Injury in the Early Phase of Acute Lymphoblastic Leukemia Induction Therapy due to Aspergillus Fumigatus and Pneumocystis Jirovecii Co-Infection: A Case Report
Author/Authors :
Sedighi, Parinaz Student Research Committee - Hamadan University of Medical Sciences, Hamadan - Universal Scientific Education and Research Network (USERN), Tehran , Esfahani, Hossein Department of Pediatrics - Faculty of Medicine - Hamadan University of Medical Sciences, Hamadan
Abstract :
Leukemia is the most common malignancy in children which leads to
immunosuppression and predisposes patients to opportunistic infections.
We report a 12-year-old girl with acute lymphoblastic leukemia (ALL) who
developed simultaneous infection with pneumocystis Jirovecii pneumonia and
aspergillosis in the induction phase of chemotherapy. The patient developed
pulmonary cavitation and pneumothorax which was treated with trimethoprimsulfamethoxasole
in addition to intravenous liposomal Amphotrecin B.
Pediatric oncologists should consider concurrent co-infection of opportunistic
infections such as aspergillus fumigatus and Pneumocystis Jirovecii in
immunocompromised patients especially if pneumothorax develops in early
stages of disease or immunosuppressive therapy.
Keywords :
Acute Lymphoblastic Leukemia , Aspergillus Fumigatus , Pneumocystis Jirovecii Pneumonia , Pneumothorax , Cavitation
Journal title :
Astroparticle Physics
