Comparison of antibacterial activities of Salvia sp. and Ballota platyloma extracts on pathogenic bacteria

Salvia and Ballota genus of Lamiaceae have been used in traditional medicine. In this study, the antibacterial effects of extract of two Salvia and Ballota plants from Lamiaceae on the pathogenic gram-positive (Bacillus cereus and Staphylococcus aureus) and gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli) have studied. For evaluating these effects, two methods, Disc diffusion and microbroth dilution have been used. In the each used two methods, extracts have demonstrated the maximum effect on the gram-positive bacteria and the minimum effect on the gram-negative bacteria. In the disc diffusion method, the largest inhibition zone of with 185 mm diameter has distinguished from the effect of Salvia extract with 200 mg/ml concentration against Staphylococcus ureus bacteria. Salvia extract with owning values MIC=2 mg/ml and MBC=4 mg/ml against Bacillus cereus, has displayed very good result. Due to the strong antibacterial effect of Salvia extract on Staphylococcus aureus and Bacillus cereus in this research, it is recommended that additional studies be done on it in the treatment of bacterial infections and food poisoning.