Author/Authors :
Dadashi, Masoud Department of Microbiology - School of Medicine - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Amjadi Kashani, Mina Department of Microbiology - School of Medicine - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Eslami, Gita Department of Microbiology - School of Medicine - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Goudarzi, Hossein Department of Microbiology - School of Medicine - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Fallah, Fatemeh Pediatric Infections Research Center - Mofid Children's Hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Owlia, Parviz Molecular Microbiology Research Center (MMRC) - Shahed University, Tehran , Adhami, Nafiseh Islamic Azad University of Pharmaceutical Sciences, Tehran , Mousavi, Tahoora Student in Research Committee - Molecular and Biology Research Center - Faculty of Mazandaran - Mazandaran University of Medical Sciences, Sari
Abstract :
Vaginitis is an inflammatory and infectious disease in human host that involved
vaginal mucosa. Increase of resistance to various antibacterial agent has been very
significant in three or four recent decades and this important subject reveals the use
of new and natural sources such as plants with medical and antimicrobial property
for eradication of these infections. Therefore, the aim of this study is to evaluate the
antibacterial effect of green tea plant on vaginitis agents.This experimental study
was performed on 60 samples obtained from patients with genital infection. Then,
samples were introduced to transport medium and transported to microbiology
laboratory of Shahid Beheshti University of Medical Science. Incubation was
performed after culturing the samples in specific medium. Microorganisms were
identified responsible for vaginitis and isolated after growth of colonies and
performing the confirmation tests. Finally, disk diffusion and MIC tests were
performed for detection of susceptibility and resistance of infections to 6 mentioned
antibiotics in comparison with green tea extract. The antibacterial effect of green tea
extract on lactobacillus and listeria was more effective in comparison with current
antibiotics except ciprofloxacin. Green tea extract had antibacterial effect on B
group streptococcus as like as gentamicin and ampicillin. Green tea extract can be
used as an effective antimicrobial agent in conjunction with other antibiotics for the
treatment of vaginal infections in women.
Keywords :
Vaginitis , Green tea , extract , Antibiotic susceptibility , infection