Title of article :
H6P2W18O62: A Green and Reusable Catalyst for the One-pot Three-Component Synthesis of Spirooxindoles in Water
Author/Authors :
Lasemi, Zahra Department of Chemistry - Firoozkooh Branch, Islamic Azad University, Firoozkooh , Mehrasbi, Ebrahim Department of Organic Chemistry - Faculty of Chemistry - University of Mazandaran, Babolsar
Abstract :
Wells–Dawson tungsten heteropolyacid (H6P2W18O62) has been applied as an effective heterogeneous catalyst for one-pot synthesis of spiro[4H-pyran-3,3’-oxindoles] via reaction of various isatins, malonitrile and 1,3-dicarbonyl compound in water. The corresponding products were obtained in high yields. The catalysts were easily recycled and reused without loss of their catalytic activity.
Keywords :
Heteropolyacids , Spirooxindole , Multi-component reaction , Aqueous medium , 1, 3-dicarbonyl compound
