Nano SnCl2-SiO2 Catalyzed Facile Synthesis of Aryloylamido Coumarins Derivatives

A highly efficient and general method for the synthesis of aryloylamido coumarins derivatives by a three-component condensation of 4-hydroxycoumarin or 4-hydroxy-6- methylpyran-1-one, aryl glyoxals and benzamide in the presence of nano silica supported tin (II) chloride as a heterogeneous catalyst is established. In this method, SnCl2/nano SiO2 was used as green and reusable catalyst. Excellent yields, short reaction times, simple workup, and inexpensiveness and commercially availability of the catalyst are the advantages of this method.