Title of article :
Coupling of Amines, Dialkyl acetylenedicarboxylaes and Formaldehyde Promoted by Copper (II) Chloride: An Efficient Synthesis of Polysubstituted Dihydro-2-oxopyrrols
Author/Authors :
Lashkari, Mojtaba Faculty of Science - Velayat University, Iranshahr , Heydari, Reza Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Mohamadpour, Farzaneh Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan
Abstract :
An environmental friendly synthetic route for copper (II) chloride dihydrate catalyzed one-pot multicomponent synthesis of biologically active high substituted dihydro-2-oxypyrroles has developed. The non-toxic, low-cost catalyst and eco-friendly and good to high yields are the notable benefits for the efficient synthesis of these products.
Keywords :
Copper (II) chloride dihydrate , Polysubstituted dihydro-2-oxypyrroles , Multi-component reaction , Environmentally benign procedure
