Title of article :
A Simple, Practical and Efficient Method for the Synthesis of New Disubstituted 1,3,4-oxadiazoles
Author/Authors :
Ramazani, Ali Department of Chemistry - University of Zanjan, Zanjan , Zamanesazi, Delnia Department of Chemistry - Payame Noor University, Tehran , Ahmadi, Yavar North West Reseach Complex - Nuclear Science and Technology Research Institute, Bonab , Azimzadeh Asiabi, Pegah Department of Chemistry - University of Zanjan, Zanjan , Souldozi, Ali Department of Chemistry - Urmia Branch - Islamic Azad University, Urmia , Woo Joo, Sang School of Mechanical Engineering - Yeungnam University, Republic of Korea
Abstract :
Reactions of N-isocyaniminotriphenylphosphorane with α- chloroketones in the presence of aromatic carboxylic acids proceed smoothly at room temperature and in neutral conditions to afford new disubstituted 1,3,4-oxadiazole derivatives in high yields.
Keywords :
N-isocyaniminotriphenylphosphorane , aromatic carboxylic acid , α- chloroketone , 1, 3, 4-oxadiazole , aza-Wittig reaction
