Title of article :
Three-component Process for the Synthesis of Some Thiophene Derivatives Using Water as a Green Media
Author/Authors :
Varasteh Moradi, Ali Department of Chemistry - Gorgan Branch, Islamic Azad University, Gorgan
Abstract :
A convenient and efficient three-component reaction to a one-pot synthesis of thiophene derivatives from activated acetylenic compounds and ethyl 2chloroacetoacetate in the presence of tetramethyl thiourea in water lead to the formation of thiophenes in good yields.
Keywords :
One-pot reactions , Tetramethyl thiourea , Ethyl 2-chloroaceto acetate
