Title of article :
Synthesis of Thiazole Derivatives via Multicomponent Reaction of Tetramethyl thiourea using Water as a Safe Solvent
Author/Authors :
Rezvani Sani Joybari, Masoud Department of Chemistry - Qaemshahr Branch, Islamic Azad University, Qaemshahr , Hossaini, Zinatossadat Department of Chemistry - Qaemshahr Branch, Islamic Azad University, Qaemshahr
Abstract :
An efficient synthesis of 1,3-thiazole drivatives is described via a three component reaction isothiocyanates, tetramethyl thiourea and ethyl bromopyruvate.
Keywords :
1,3-Thiazole , Benzoyl isothiocyanate , Ethyl bromopyruvate , Tetramethyl thiourea , Ammonium thiocyanate , Acid chloride
