Title of article :
A One-Pot Synthesis of Highly Functionalized Ketenimines by a Three-component 2-Thioxothiazolidin-4-one, Alkyl Isocyanides and Dialkyl Acetylenedicarboxylates
Author/Authors :
Yadollahzadeh, Khadijeh Department of Chemistry - Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul
Abstract :
The 1:1 reactive intermediates produced in the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates were trapped with 2-thioxothiazolidin-4-one to generate to highly functionalized ketenimines. A series of new 2-thioxothiazolidin-4-one derivatives were synthesized in moderate yields. The advantages of the present method include good functional group tolerance and simple experimental procedure and purification.
Keywords :
Ketenimines , 2-Thioxothiazolidin-4-one , Acetylenic esters , Isocyanides
