Title of article :
A Rare Case Report of Postmenopausal Virilization: Ovarian Steroid Cell Tumor
Author/Authors :
Ebrahimpur, Mahbube Shariati Hospital - Tehran University of Medical Sciences , Mohajeri-Tehrani, Mohammad Reza Endocrinology and Metabolism Clinical Science Institute - Tehran University of Medical Sciences , Saffar, Hiva Shariati Hospital - Tehran University of Medical Sciences , Pejman Sani, Mahnaz Shariati Hospital - Tehran University of Medical Sciences
Abstract :
Ovarian steroid cell tumors are rare, life-threatening neoplasms that make about 0.1% of all primary ovarian tumors. They frequently present in premenopausal women with the manifestation of virilization. We report a 58-year-old postmenopausal woman that referred to our clinic with clinical manifestation of virilization. Laboratory findings showed markedly elevated serum testosterone level and ultrasound showed 2 follicles with 7 mm diameters in the left ovary. She treated by bilateral salpingo-oophorectomy and synchronous hysterectomy. Histological pathology confirmed a benign steroid cell tumor. The presentation of new-onset and rapid progressive hyperandrogenism is rare in postmenopausal women. In diagnosis, we must consider adrenal and ovarian malignancies. Stromal luteoma is a rare benign ovarian tumor, Which is treated with surgical treatment.
Keywords :
Hyperandrogenism , Postmenopause , Stromal luteoma
Journal title :
Acta Medica Iranica