Author/Authors :
Byun, Seonghwan Department of Radiology - Soonchunhyang University Hospital Bucheon - Bucheon, South Korea , Shin, Kyung Eun Department of Radiology - Soonchunhyang University Hospital Bucheon - Bucheon, South Korea , Park, Jai Soung Department of Radiology - Soonchunhyang University Hospital Bucheon - Bucheon, South Korea , Lee, Heon Department of Radiology - Soonchunhyang University Hospital Bucheon - Bucheon, South Korea , Lee, JaeWook Department of Radiology - Soonchunhyang University Hospital Bucheon - Bucheon, South Korea , Chin, Susie Department of Pathology - Soonchunhyang University Hospital Bucheon - Bucheon, South Korea , Koh, Eun Suk Department of Pathology - Soonchunhyang University Hospital Bucheon - Bucheon, South Korea
Abstract :
Immunoglobulin G4-related disease is a novel inflammatory entity involving multiple organs of the body. In the lungs, it is accompanied
by infiltration of IgG4-positive lymphocytes and increased serum levels of IgG4. Previous studies have reported radiological
findings of IgG4-related lung disease in the pulmonary parenchyma; however, there are few case reports of pleural involvement.
Here, we report the case of a 66-year-old man with IgG4-related disease unilaterally involving the lung interstitium and pleura.
Thoracic computed tomography images demonstrated pleural effusion and thickening resembling a primary or secondary pleural
malignancy. The diagnosis of IgG4-related disease was confirmed by video-assisted-thoracoscopic biopsy. This rare disease should
not be overlooked in patients with radiological findings that are suggestive of pleural malignancies.
Keywords :
Immunoglobulin G , Pleural Disease , Pleural Effusion , Plasma Cells
