Title of article :
Advanced Virtual Monochromatic Images from Dual Source Dual-Energy CT for a Reduction in the Contrast Medium Dose (389 mgI/kg) in Multiphase Liver CT: Evaluation of Image Quality and Focal Lesion Conspicuity
Author/Authors :
Kim, Ji Eun Department of Radiology - Gyeongsang National University Hospital - Gyeongsang National University College of Medicine - Jinju, South Korea , Kim, Hyun Ok Department of Internal Medicine - Gyeongsang National University College of Medicine and Gyeongsang National University Hospital - Jinju, South Korea , Bae, Kyungsoo Department of Radiology - Gyeongsang National University Hospital - Gyeongsang National University College of Medicine - Jinju, South Korea , Cho, Jae Min Department of Radiology - Gyeongsang National University Hospital - Gyeongsang National University College of Medicine - Jinju, South Korea , Choi, Ho Cheol Department of Radiology - Gyeongsang National University Hospital - Gyeongsang National University College of Medicine - Jinju, South Korea , Choi, Dae Seob Department of Radiology - Gyeongsang National University Hospital - Gyeongsang National University College of Medicine - Jinju, South Korea , Na, Jaebeom Department of Radiology - Gyeongsang National University Hospital - Gyeongsang National University College of Medicine - Jinju, South Korea
Abstract :
Background: Low-energy advanced virtualmonochromaticimages (VMIs)from dual source dual-energy CT (DSCT) could be applied
to reduce contrast medium dose due to superior iodine contrast-to-noise ratios (CNRs).
Objectives: To investigate feasibility of advanced VMIs from DSCT to reduce contrast medium dose in multiphase liver CT without
impairing image quality and conspicuity of focal hepatic lesions (FHLs).
Patients and Methods: Ninety-four patients with 110 FHLs underwent follow-up CT twice prospectively with different protocols:
protocol A, conventional 100 kVp and 555 mgI/kg; protocol B, dual-energy mode and 389 mgI/kg. The signal-to-noise ratio (SNR)
and lesion-to-liver CNR were compared between the VMIs (40 - 120 keV, 10-keV interval) reconstructed using advanced image-based
algorithm and conventional images. Two radiologists qualitatively evaluated VMIs, compared with the 100 kVp images, using a
six-point scale.
Results: The SNRs of pancreas, aorta, portal and hepatic vein were similar to those at 100 kVp images (P > 0.05) at 40-50 keV images
during late arterial phase (LAP) and at 40-60 keV images during portal venous phase (PVP) except for the SNRs of aorta and veins at
40 keV images which were significantly higher (P < 0.0109) during both phases and PVP, respectively. The CNR of 56 hypervascular
FHLs was significantly higher at 40 - 50 keV images (P < 0.0002) and was similar at 60 keV images (P > 0.05) during LAP. The CNR
of 58 hypovascular FHLs was similar at 40 - 120 keV images (P > 0.05) during PVP. Among the VMIs, 50 keV and 50 - 60 keV images
received the highest scores (P < 0.0315 and P < 0.0041) by both reviewers during LAP and PVP, respectively.
Conclusion: Advanced 50 - 60 keV images from DSCT allowed contrast dose reduction by 30% in multiphase liver CT without impairing
image quality and conspicuity of FHLs, compared with the conventional 100 kVp images with 555 mgI/kg.
Keywords :
Contrast Medium , Computed Tomography , Dual-Energy , Virtual Monochromatic Image
Journal title :
Iranian Journal of Radiology (IJR)
