Effect of Circuit Resistance Training and L-Carnitine Supplementation on Body Composition and Liver Function in Men with Non-Alcoholic Fatty Liver Disease

background: exercises and l-carnitine supplementation are effective for liver function. objectives: the purpose of this study was to compare effect of circuit resistance training and l-carnitine supplementation on body composition and liver function in men with non-alcoholic fatty liver disease (nafld). methods: in this semi-experimental study, 40 men with nafld were selected through purposive sampling and were randomly assigned to one of four groups includes: (1) resistance training, (2) supplement, (3) combined (exercise- supplement) and (4) control. circuit resistance training was performed for 12 weeks, three sessions per week, with a training intensity of 40% - 80% maximum one-repetition. in the combined and supplementation group, 10 mg l-carnitine supplement per kg body weight was consumed daily with three main meals. to analyze the data, dependent t-test and one-way analysis of variance were used at p ≤ 0.05. results: after exercise, there was a significant decrease in body mass index and body fat percentage in the resistance training group and combined (exercise-supplement) group when compared to the control and supplementation groups. there was also a significant decrease in the level of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in the intervention groups including exercise, supplement, and combined (exercise-supplement) groups compared to the control group. the percentage of changes in ast and alt was significantly higher in the combined group than in the training and supplement groups. conclusions: according to the findings of this study, circuit resistance and complementary l-carnitine training are effective for improving liver function. this improvement was more evident in the combination of training and l-carnitine supplementation, and these shifts are independent of changes in body composition.