Effect of eight weeks circuit resistance training with Zataria multiflora supplementation on plasma levels of leptin and adiponectin in postmenopausal women

Introduction: Aging and low physical activity results in a decrease in Adiponectin and an increase in leptin, which can cause cardiovascular diseases, obesity and diabetes. The aim of present study was to investigate the effect of 8 weeks circuit-resistance training (CRT) with Zataria multiflora (Z. multiflora) supplementation on plasma leptin and adiponectin in postmenopausal women. Materials and methods: 48 untrained postmenopausal women took part in this study. The participants were randomly divided in 4 groups with 12 persons in each: resistance training (RTG), Z. multiflora (ZG), control (CG) and Z. multiflora- resistance training (ZRTG). Resistance training program contained 12 stations (each station 30 second with 35 percent of one maximum repetition) and continued for 8 weeks (3 sessions per week). Participants in the ZG and ZRTG consumed 500 mg of Z. multiflora supplementation daily before breakfast. Blood samples were collected 48 hours before first session and 48 hours after last session to measure plasma levels of leptin and Adiponectin. Results: Significant difference between ZRTG and CG in plasma Adiponectin was observed (P˂0.05). However, there was no significant difference between groups in leptin (P˃0.05). Conclusion: This study indicated that CRT can cause a decrease in leptin and an increase in Adiponectin. Also, when Z. multiflora intervention included in the training program, this effects increased.