Author/Authors :
Mozaffari, A Medical Physics Department - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Ghorbani, M Medical Physics Department - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran
Abstract :
Objective: Brachytherapy sources are widely used for the treatment of cancer.
The report of Task Group No. 43 (TG-43) of American Association of Physicists in
Medicine is known as the most common method for the determination of dosimetric
parameters for brachytherapy sources. The aim of this study is to obtain TG-43
dosimetric parameters for 60Co, 137Cs, 192Ir and 103Pd brachytherapy sources by Monte
Carlo simulation.
Methods: In this study, 60Co (model Co0.A86), 137Cs (model 6520-67), 192Ir (model
BEBIG) and 103Pd (model OptiSeed) brachytherapy sources were simulated using
MCNPX Monte Carlo code. To simulate the sources, the exact geometric characterization
of each source was defined in Monte Carlo input programs. Dosimetric
parameters including air kerma strength, dose rate constant, radial dose function and
anisotropy function were calculated for each source. Each input program was run
with sufficient number of particle histories. The maximum type A statistical uncertainty
in the simulation of the 60Co, 137Cs, 192Ir and 103Pd sources, were equal to 4%,
4%, 3.19% and 6.50%, respectively.
Results: The results for dosimetry parameters of dose rate constant, radial dose
function and anisotropy function for the 60Co, 137Cs, 192Ir and 103Pd sources in this
study demonstrated good agreement with other studies.
Conclusion: Based on the good agreement between the results of this study and
other studies, the TG-43 results for Co0.A86 60Co, 67-65200 137Cs, BEBIG 192Ir and
OptiSeed 103Pd sources are validated and can be used as input data in treatment planning
systems (TPSs) and to validate the TPS calculations.
Keywords :
103Pd , 192Ir , 137Cs , 60Co , Monte Carlo Method , TG-43 dosimetric Parameters , Brachytherapy