The Clinical Indications and Cytogenetic Analysis of Genetic Amniocentesis Cases

Prenatal genetic screening tests are planned to screen for structural abnormalities, aneuploidy, and genetic diseases in the prenatal period. The prevalence of genetically modified disorders in neonates is estimated to be 4%, and the risk increases with increasing maternal age (1). Down syndrome is one of the most prevalent genetic diseases affecting about 1 in 400 - 1500 newborns, and the risk increaseswith increasingmaternal age(2). Screening for this syndrome is recommended to all pregnant women, especially in women 35 years of age and older.