Title of article :
Supplementation with omega-3 plus vitamin E and zinc plus vitamin C on metabolic syndrome components in postmenopausal women with type 2 diabetes
Author/Authors :
Mahmoodi, Mohammad Reza Physiology Research Center - Institute of Basic and Clinical Physiology & Nutrition Department - School of Health - Kerman University of Medical Sciences , Mehrabi, Yadollah Department of Health and Social Medicine - School of Medicine - Shaheed Beheshti University of Medical Sciences. Tehran , Kimiagar, Masoud Human Nutrition & Diet Therapy Department - School of Nutrition and Food Technology - Shaheed Beheshti University of Medical Sciences. Tehran , Rajab, Asadollah Iranian Diabetes Society - Malakotti St, Tehran
Pages :
12
From page :
43
To page :
54
Abstract :
Background: The aim of this study was to find the influence of supplementation with omega-3 plus vitamin E and vitamin C plus zinc on metabolic syndrome components. Methods: In a double-blind controlled clinical trial, 75 diabetic postmenopausal women were randomly assigned to one of the three therapeutic groups of daily supplementation of 1.8g omega-3 plus 400mg vitamin E (group A), 5mg zinc plus 300mg vitamin C (group B), or placebo (group C) for 12 weeks and the results were evaluated. Results: One-way repeated measures ANOVA showed that systolic and diastolic blood pressure and waist circumference showed significant difference before and after the intervention (P= 0.0001, 0.001, and 0.045, respectively). Results of Univariate ANOVA showed that the level of plasma fasting blood sugar (FBS) and HDL-cholesterol significantly increased (P=0.01 and P=0.03, respectively) in patients who had been diagnosed as diabetic ≤7 years in group B. The plasma TG concentration significantly decreased (P=0.007) in patients who had been diagnosed as diabetic ≤7 years in group A. Systolic and diastolic BP significantly decreased (P=0.005 and P=0.04, respectively) in patients who had been diagnosed as diabetic ≤7 years in group A. The most effectiveness of nutraceutical supplementation was on patients that had been diagnosed as diabetic ≤7 years. Plasma TG and systolic BP decreased with omega-3 plus vitamin E; however, plasma FBS and HDL- cholesterol increased with zinc plus vitamin C supplementation. Conclusion: Several factors, such as duration of diabetes, age, gender, pathophysiology status, genetic, and other anthropometric characteristics may influence the effectiveness of supplementation.
Keywords :
Metabolic syndrome components , Postmenopausal women , Supplementation , Type 2 diabetes
Journal title :
Journal of Kerman University of Medical Sciences (JKMU)
Serial Year :
2019
Record number :
2501339
Link To Document :
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