Author/Authors :
Bajelan, Mansoureh Cellular and Molecular Research Centre - Iran University of Medical Science, Tehran, Iran , Etehad Roodi, Negar Cellular and Molecular Research Centre - Iran University of Medical Science, Tehran, Iran , Hasanzadeh Daloee, Mahdy Department of Tissue Engineering & Regenerative Medicine - Iran University of Medical Science, Tehran, Iran , Farhangnia, Mansoureh Cardiovascular Research Center - Ghaem Hospital - Mashhad University of Medical Sciences, Iran , SamadiKuchaksaraei, Ali Cellular and Molecular Research Centre - Iran University of Medical Science, Tehran, Iran
Abstract :
Background: Age-related morbidity and mortality rates from coronary heart disease (CHD) are higher in men
than in women. Abnormal androgen levels cause a variety of abnormal symptoms in men. Testosterone and
estrogen are the main sex hormone in men and women, respectively, and studies have shown that they have
important roles in cardiovascular health and disease.
Methods:We measured testosterone and estrogen in 102 men with coronary heart disease and 45 controls. Blood
samples were collected from subjects and plasma testosterone and estrogen were measured by ELISA.
Results:Men with coronary heart disease had less testosterone (OD Ratio: 0.782) and estrogen (OD Ratio: 0.955)
than controls.
Conclusions:Low testosterone and estrogen levels correlate with coronary artery disease.
