Seroprevalence of Hepatitis B&C in coronary artery disease patients in an Iranian population

Background: Coronary artery disease (CAD) is one of the main causes of death all over the world. Predisposing factors comprise some infectious etiologies with systemic effects such as the hepatitis C virus and HBV-infection might be related to CAD from chronic inflammation process. The relationships between hepatitis B&C virus (HBV&HCV) infections and CAD considered a noticeable health problem. In the present study, we evaluated the seropositivity of HCV&HCB in CAD patients from the Iranian population. Materials and Methods: We conducted a cohort study including 192 CAD subjects. To identify HCV&HCB -infected subjects, a serologic examination comprising Hepatitis B surface antigen (HBsAg) and anti-HCV antibodies (HCV-Ab) tests performed by ELISA method. Also, we examined the biochemical blood parameters such as lipid profile, glycemic parameters, and blood inflammatory factor (C-reactive protein). Results: We identified a very low percent of HBV-infected cases (1.04%). All examined CAD patients indicate the HCV Ab-negative results. The HBV-infected subject had not, hyperlipidemia, and diabetes. HBV infection was not related to the increased risk of CAD. Also, CAD risk factors were not associated with the prevalence of HBV&HCV. Conclusion: According to the results, HCV&HCB infections had very low prevalence in examined subjects and there was not any association between CAD and prevalence of HCV&HCB infections.