Author/Authors :
Madadi, Firoozeh Anesthesiology Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Hekmat, Manouchehr Department of Cardiac Surgery - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Ansari Aval, Zahra Department of Cardiac Surgery - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Bagheri, Abdolhamid Cardiovascular Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Fani, Kamal Anesthesiology Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Ghanbarpour, Mohammad Hosein Anesthesiology Department - School of Medicine - Zanjan University of Medical Sciences, Zanjan, Iran , Hamidzad, Maryam Cardiovascular Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Murodov, Mehrubon Republican Scientific Center of Cardiovascular Surgery - Dushanbe, Tajikistan , Dabbagh, Ali Anesthesiology Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
Background: Aortic dissection is a rare yet life threating condition with some already discovered risk factors namely hypertension, connective tissue disorders such as Marfan syndrome (MFS), cocaine abuse and cigarette smoking.Case report: In this article we would like to present a case of MFS who presented with severe chest pain and undergone Bentall surgery due to aortic dissection and aneurysm.Conclusion: Although many risk factors and preventive measures are already investigated, there is no definite method to avoid its occurrence in genetically predisposed patients such as MFS. Patient-specific models utilizing embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) may offer some advantages.
Keywords :
Marfan syndrome , Aortic dissection , iPSC , cocaine