Title of article
Pachydermoperiostosis: A clinicopathological description
Author/Authors
Tabatabaei Ali Ocular Trauma and Emergency Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran , Masoomi Ahmad Ocular Trauma and Emergency Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran , Soleimani Mohammad Ocular Trauma and Emergency Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran , Rafizadeh Mohsen Ocular Trauma and Emergency Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran , Salabati Mirataollah Ocular Trauma and Emergency Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran , Ahmadraji Aliasghar Ocular Trauma and Emergency Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran , Bohrani Bahram Ocular Trauma and Emergency Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran , Ghahvechian Hossein Ocular Trauma and Emergency Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran , Nozarian Zohreh Pathology Department - Farabi Eye Hospital - Tehran University of Medical Sciences - Tehran, Iran
Pages
4
From page
450
To page
453
Abstract
To report a case of pachydermoperiostosis (PDP) and a review of the literature.
Methods: A 32-year-old man was referred to our clinic with bilateral eyelid swelling and blepharoptosis. On examination, marked blepharoptosis
was noted, and his eyelids were found to be floppy. Systemic examination was significant for clubbing of digits, coarse acromegalic facial
features, and furrowing and oiliness of the skin of scalp and forehead.
Results: The patient was diagnosed as a case of PDP. On the brain MRI, the pituitary gland was enlarged, and the border of clivus was irregular.
Pituitary and thyroid hormone levels were normal. He underwent bilateral lateral tarsal strip (LTS) procedure to address the eyelid laxity.
Histopathologic examination revealed marked sebaceous gland hyperplasia with mucin deposition in the dermis.
Conclusion: Floppy eyelid syndrome, clubbing, and acromegaloid face are main features that could lead to the diagnosis of PDP.
Keywords
Floppy eyelid syndrome , Acromegaloid face , Clubbing , Pachydermoperiostosis
Journal title
Journal of Current Ophthalmology
Serial Year
2019
Record number
2503428
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