Title of article :
The Prevalence of Human Herpes Virus Type 8 in Semen Specimens of HIV-Negative Iranian Population Detected by Nested Polymerase Chain Reaction
Author/Authors :
Rakhshan ، Azadeh Pathology Department - Men s Health and Reproductive Health Research Center, School of Medicine - Shahid Beheshti University of Medical Sciences , Moradi ، Afshin Pathology Department - Men s Health and Reproductive Health Research Center, School of Medicine - Shahid Beheshti University of Medical Sciences , Ahadi ، Mahsa Pathology Department - Men s Health and Reproductive Health Research Center, School of Medicine - Shahid Beheshti University of Medical Sciences , Rezaei ، Mitra Sadat Pathology Department - School of Medicine, Virology Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD) - Shahid Beheshti University of Medical Sciences , Jamali ، Elena , Kazeminejad ، Behrang Pathology Department - Men s Health and Reproductive Health Research Center, School of Medicine - Shahid Beheshti University of Medical Sciences , Mollasharifi ، Tahmineh Pathology Department - Men s Health and Reproductive Health Research Center, School of Medicine - Shahid Beheshti University of Medical Sciences , Hosseini ، Jalil Men s Health and Reproductive Health Research Center - Shahid Beheshti University of Medical Sciences , Movafagh ، Abolfazl Men s Health and Reproductive Health Research Center - Shahid Beheshti University of Medical Sciences , Moradi ، Arsham Department of Biology - University of Toronto , Aliakbari ، Fereshteh Men s Health and Reproductive Health Research Center - Shahid Beheshti University of Medical Sciences
Abstract :
Background: Human herpesvirus type 8 (HHV-8) is a member of the herpes family that, like other herpesviruses, causes a lifelong infection following entrance into the human body. The etiological agent of Kaposi’s sarcoma, this virus, was first identified in a biopsy of a Kaposi’s sarcoma tumor in an HIV-infected patient. Objectives: The aim of this research was to evaluate the prevalence of HHV-8 in semen specimens from HIV-negative individuals. Methods: Semen specimens obtained from HIV-negative individuals referred to an infertility center were transferred to the central laboratory for HHV-8 DNA amplification via the nested polymerase chain reaction (PCR) technique. Results: The prevalence of HHV-8 in the referral population was 26%. Conclusions: The prevalence of HHV-8 in the semen samples of our study population may be representative of its prevalence in the normal population. Further studies are, therefore, recommended to determine the prevalence of the virus in the normal Iranian population.
Keywords :
Semen Analysis , HIV , Human Herpesvirus 8 , Nested PCR , Kaposi’s Sarcoma
Journal title :
International Journal of Cancer Management
Journal title :
International Journal of Cancer Management
