Title of article :
Comparison of Ketamine and Tramadol in Management of Acute Pain; a Systematic Review
Author/Authors :
Naghipour, Bahman Department of Anesthesiology and Critical Care - Tabriz University of Medical Sciences, Tabriz , Pouraghaei, Mahboub Tabriz University of Medical Sciences, Tabriz , Tabatabaey, Ali Department of Emergency Medicine - Islamic Azad University, Tehran , Arjmand, Allahveirdy Department of Anesthesiology - Maragheh University of Medical Sciences, Maragheh , Faridaalaee, Gholamreza Department of Emergency Medicine - Maragheh University of Medical Sciences, Maragheh
Abstract :
Introduction: Management of pain is an important part of care in the emergency department (ED). Tramadol
and Ketamine have both been introduced as alternatives to opioids in the ED and post-operative setting. In
this study, we conducted a systematic review of available literature to compare the analgesic efficacy, and side
effect profile of these two medications in management of severe acute pain. Methods: This is a systematic
review based on the PRISMA protocol. In this study, peer-reviewed papers published by March 3, 2020, which
compared analgesic effects of tramadol and ketamine in management of acute pain were included. Results: The
initial search of online databases identified 2826 non-duplicate records. Finally, three papers available in full text
were analyzed for study quality. The results show that ketamine has consistently been shown to be superior to
tramadol for pain control and causes fewer significant side effects. Conclusion: Results of this review show that
low-dose ketamine is more effective than tramadol in pain control, while causing fewer side effects.
Keywords :
Ketamine , Tramadol , pain management , emergency treatment , acute pain
Journal title :
Archives of Academic Emergency Medicine (AAEM)
