Author/Authors :
Hashemzehi ، Milad Department of Medical Physiology - Faculty of Medicine - Mashhad University of Medical Sciences , ShahidSales ، Soodabeh Cancer Research Center - Mashhad University of Medical Sciences , Hassanian ، Mahdi Department of Medical Biochemistry - Faculty of Medicine, Metabolic syndrome Research center - Mashhad University of Medical Sciences , Joudi Mashhad ، Mona Cancer Research Center - Mashhad University of Medical Sciences , Avan ، Amir Department of Modern Sciences and Technologies - School of Medicine, Metabolic syndrome Research center - Mashhad University of Medical Sciences , Khazaei ، Majid Department of Medical Physiology - Faculty of Medicine - Mashhad University of Medical Sciences
Abstract :
Breast cancer is among the most common types of cancer and the second leading cause of cancer-related death in women. Therefore, finding treatments with the highest effectiveness and least side effects is of great importance. Curcuma langa, commonly known as curcumin, has many advantages, including antioxidant, antiinflammatory, anticancer, and wound-healing properties. The anticancer mechanisms include prevention of malignant cell formation, as well as reduction of angiogenesis and tumor growth, as documented in some malignancies, including pancreatic, ovarian, gastric, and colorectal cancers. Recent research has also documented curcumin activities against breast cancer, in particular molecular pathways involved in cell growth, differentiation, apoptosis, and suppression of inflammation. Therefore, the aim of the current review was to study the effects of curcumin on breast cancer. Conflicts of Interest: The authors declare no conflicts of interest.
