Retrospective Epidemiological Study of Malaria from 1999 to 2016 in Khash, Iran: A Region on the Verge of Malaria Elimination

strong Background: /strong Malaria infection is still one of the most important public health concerns globally. The aim of this study was to evaluate retrospective epidemiological study of malaria in Khash City, Sistan and Baluchestan Province of Iran from 1999 to 2016. br / strong Methods: /strong This was a retrospective study, which collected official data of 26year trend of malaria in Khash, Sistan and Baluchestan Province of Iran. br / strong Results: /strong The data showed that over 26 years, 5015 cases of malaria were identified in Khash; the highest number of cases was reported in 1995 with 846 patients and the lowest number was in 2016 with one patient. A total of 419 patients were Iranian (52.2%) and 383 patients (47.8%) were nonIranian including: Afghans (323 patients, 40.3%) and Pakistanis (60 patients, 7.5%).  During 17 years, 279200 blood slides for malaria were prepared in Khash of which 5014 slides were found to be positive. The highest and lowest ABER were in 20032004 (63.69) and 20162017 (0.30), respectively. em Plasmodium vivax /em was identified as the main and dominant causative agent of disease in all infected patients. br / strong Conclusions: /strong The results revealed a significant decline in malaria incidence rate in Khash. However, based on Iran’s vast borders with malaria endemic countries (Afghanistan and Pakistan) and illegal immigrants coming from these nations to country, the risk of malaria outbreaks must be considered seriously and the control and/or screening programs should be conducted constantly until the complete elimination of the infection.