Molecular and Phenotypic Characteristics of Staphylococcus Hominis Isolates From Pediatric Infections

Background: em Staphylococcus hominis /em has been recently emerged as an opportunistic hospitalassociated pathogen. The aim of this study was to characterize the antimicrobial susceptibility pattern, biofilm formation, and staphylococcal cassette chromosome em mec /em (SCC em mec /em ) types among clinical isolates of em S. hominis /em obtained from pediatric infections. Methods: Totally, twenty two clinically significant em S. hominis /em isolates, mostly from blood samples, were examined for antibiotic resistance, SCC em mec /em typing, and biofilm formation.  Results: Multiresistance was observed in 86 % of isolates. Among em mec /em A positive isolates (77%), SCC em mec /em type I (28%), III (22%), IV (22%), and nontypeable ones (28%) were detected. More than half of the isolates (54.5%) did not produce biofilm. No significant association was found between biofilm formation and the presence of em ica /em operon. Conclusion: As em S. hominis /em isolates were not strong biofilm producers, biofilm formation cannot be considered as much as important multidrug resistance.in the pathogenesis of isolates.