Risk factors for prostate cancer: A case control study

Background: Prostate cancer is the second leading cause of cancer-related death in men. The aim of this study was to examine the association between the prostate cancer and the possible etiological agents. Methods: In a case-control study, 60 men with prostate cancer who were between 40 to 65 years of age were studied over the period between March 2013 and May 2016. For each prostate cancer case, there was a control, who was matched in terms of age and residence. The demographic factors of the men with prostate cancer were compared with those of the healthy cases as a control group. Results: After adjusting the variables, the obesity (BMI ≥ 25) (OR= 16.07, 95% CI= 4.90-52.67), the sitting height ≥ 111 (OR= 6.45, 95% CI= 1.87-22.23), the current use hookah (OR= 1.84, 95% CI= 0.48-7.03), and the positive family history of the prostate cancer (OR= 55.60, 95% CI= 9.04- 341.93) were found to be all associated with an increased risk of prostate cancer. Conclusion: To decrease the prostate cancer among Iranian men, more emphasis should be placed on screening programs to identify prostate cancer in men with the positive family history of cancer, the overweight ones, the ones with higher sitting height, and those who use hookah.