Title of article :
Basic Task-specific Ionic Liquid as Catalyst and Reaction Medium: A Green Protocol for the Synthesis of 4-Oxo-6-aryl-2-thioxo-1,2,3,4- tetrahydropyrimidine-5-carbonitrile Derivatives
Author/Authors :
Hasanpour, Maede Department of Chemistry - School of Sciences - Ferdowsi University of Mashhad , Eshghi, Hossein Department of Chemistry - School of Sciences - Ferdowsi University of Mashhad , Mirzaei, Mahdi Department of Chemistry - School of Sciences - Ferdowsi University of Mashhad
Abstract :
Abstract A novel basic ionic liquid based on imidazolium cation is designed, synthesized and successfully used as a catalyst for the one-pot synthesis of 4-Oxo-6-aryl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile derivatives. The remarkable features of this new catalyst are its ethyleneoxy bridge which participates in dissolving organic compound in the ionic liquid and its strong base counterion. The application of this ionic liquid is studied in a new one-pot method for the synthesis of heterocyclic compounds under solvent-free conditions. A simple and convenient procedure, high conversion, reusability of catalyst, easy purification and shorter reaction time are the advantageous features of this method.
Keywords :
Ionic Liquid , Imidazolium cation , Pyrimidine , Reusable catalyst , Ethyleneoxy bridge
Journal title :
Organic Chemistry Research
