Does Monosodium Glutamate Induce Obesity in Female Mice?

Objective: Female metabolism is highly responding towards diet associated changes. Monosodium glutamate is a popular flavor enhancer, which is widely used to develop umami taste. Young female generation nowadays deals with more issues related to metabolism and fertility. Present study is an effort to monitor the effect of monosodium glutamate oral consumption on female mice health and obesity. Materials and Methods: Adult female Swiss albino mice Mus musculus were divided into two groups named control and treatment. Treated group received 4 gm/kg body weight/day dose of monosodium glutamate dissolved in double distilled water by oral gavage. Control group received only double distilled water. After the completion of experiment, lee index was calculated to determine the induced level of obesity. Results: Present study states that lee index of monosodium glutamate treated mice were significantly higher than control mice. This increment of lee index indicates that monosodium glutamate is contributing factor for induction of obesity in female mice. Conclusion: Obesity is the main cause of metabolic syndrome, which comes with many associated feminine health issues. Our findings strongly discourage prolonged consumption of high doses of monosodium glutamate to avoid obese young female population.