Title of article :
Antioxidant and Inhibitory Activities of Enzymes Linked to Type II Diabetes Mellitus: The Novel Role of Chrysobalanus Orbicularis Leaf Extract
Author/Authors :
Lisa ، Ekakitie Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry - Afe Babalola University , Ojo ، Oluwafemi Department of Biochemistry - Landmark University , Oyinloye ، Babatunji Department of Biochemistry, Biochemical Toxicology and Biotechnology Research Laboratories, Nigeria. Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology - Afe Babalola University , Ajiboye ، Basiru Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry - Afe Babalola University
From page :
179
To page :
186
Abstract :
Background: Chrysobalanus orbicularis is commonly used as food, the seeds as a spice for the popular pepper soup, and the leaves are traditionally utilized for managing Type II Diabetes Mellitus (T2DM) in the Niger Delta area of Nigeria. Due to the limited scientific evidence on C. orbicularis, this study investigated its antioxidant and inhibitory properties against major enzymes linked to T2DM. Methods: The antioxidant activity was measured via methods for possible scavenging potentials. The alpha;amylase and alpha;glucosidase inhibitory activities were examined using a standard model. Results: The C. orbicularis aqueous leaf extract compared well with the standard compounds, revealing the high antioxidant and inhibitory properties against alpha;amylase and alpha; glucosidase. Conclusion: The findings validate the conventional application of C. orbicularis in the treatment of patients with type II diabetes mellitus and other oxidative stressrelated disorders.
Keywords :
Antioxidant activity , C. orbicularis , Diabetes mellitus , Medicinal plants
Journal title :
Iranian Journal of Toxicology
Journal title :
Iranian Journal of Toxicology
Record number :
2512507
Link To Document :
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