Fe3O4@nano-dextrin/Ti(IV) as a bio-based magnetic nano-catalyst for facile synthesis of 2,3-dihydroquinazolin-4(1H)-ones

A bio-based magnetic nano-catalyst (Fe3O4@nano-dextrin/Ti(IV)) was synthesized via the preparation of Fe3O4@nano-dextrin as magnetic support and then its treatment with titanium tetrachloride (TiCl4). The properties of this catalyst were characterized by different kinds of techniques such as FT-IR, FESEM, TEM, ICP, XRF, VSM and TGA. As a first report, the catalytic activity of Fe3O4@nano-dextrin/Ti(IV) was investigated in the synthesis of 2,3-dihydroquinazolin-4(1H)-ones via condensation between 2-aminobenzamide and aldehyde under mild conditions. Good efficiency, a high percentage of product yields, simplicity of operation and easy recovery and reuse of catalyst are some benefits of this protocol.