Biochemical changes in carbohydrate metabolism of the fish – Cyprinus carpio during sub-lethal exposure to biopesticide – Derisom.

The effect of biopesticide - Derisom on certain metabolites and enzymes of carbohydrate metabolism were evaluated in gill, liver, kidney and muscle of Cyprinus carpio during sub-lethal toxicity exposure of 21 days. A dose of 0.28 ppm was taken as the sub-lethal dose. The organs were taken from exposed and control fish at the end of 24 hrs, 7, 14 and 21 days and used for the estimation of total carbohydrates, total glycogen, succino dehydrogenase (SDH) and lactate dehydrogenase (LDH) activities. All the organs showed the significant difference between control and exposed groups in all the estimated parameters on all days of exposure. In the present study, all the parameters i.e., total carbohydrates, total glycogen, SDH and LDH significantly decreased as the days of sub-lethal exposure increased, up to the completion of 21 days of exposure. The present study considers biochemical parameters as important biomarkers in determining the level of toxicity caused by the biopesticide – Derisom.