Title of article :
Vitamin D Toxicity; Stored and Released from Adipose Tissue?
Author/Authors :
Jenabi, Arya Nephrology Research Center - Rasool Akram Hospital - Iran University of Medical Sciences , Razmjou, Sara Neuroscience Department - Carleton University - Canada , Jomhouri, Rohollah Nephrology Research Center - Iran University of Medical Sciences , Ziaie, Hossein Nephrology Research Center - Iran University of Medical Sciences
Abstract :
Vitamin D is a pro-hormone that plays an important role in body calcium regulation. Vitamin D toxicity occurs rarely due to its wide therapeutic index. A 38-year-old Iranian man was admitted to our hospital with a diagnosis of vitamin D toxicity. Laboratory test revealed hypercalcemia and elevated 25-hydroxyvitamin D (25(OH)D) level. Despite the cessation of vitamin D intake and diuretic treatment, he presented four months later with high 25(OH)D level and similar clinical features. Due to the potential release of vitamin D from adipose tissue, serial monitoring of 25(OH)D level is recommended.
Keywords :
Vitamin D , toxicity , adipose tissue
Journal title :
Archives of Iranian Medicine
