Author/Authors :
Bakhshi Aliabad, Mohammad Hossein Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Kheirandish, Shahnaz Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Zarezade, Zeynab Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Saeidi, Nasim Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Kabiri, Hamid Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Khazaei, Zahra Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Sahamifar, Hossein Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Taghvaei, Fatemeh Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Jafarzadeh, Sepideh Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Zare, Masoud Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Bahrami-Babaheidar, Sajad Faculty of Medecine - Shahid Sadoughi University of Medical Sciences - International Campus, Yazd , Mazaheri, Mahta Department of Genetics - Faculty of Medicine - Shahid Sadoughi University of Medical Sciences, Yazd
Abstract :
Micro-RNAs (miRNAs) are small molecules that modulate the translation of target mRNA
through binding to these molecules. In cancer, the expression of oncogenes and suppressors are
increased and decreased, respectively. MiRNAs are one of the causing factors in the formation
of cancer. To collect data, research articles in PubMed and Google Scholar were searched under
keywords including breast cancer and micro-RNA. The data obtained from articles published in
prestigious journals showed that some miRNAs are involved in the suppression and some in the
induction of cancer cell growth in breast cancer tissue. Some of them are also involved in the
aggression and metastasis. According to the obtained results, it seems that assessing miRNAs in
breast cancer tissue can be considered as a potential candidate for prognosis and may be used
in pre-diagnosis of the disease in near future.
