Title of article :
Drug-induced Nephrotoxicity and Medicinal Plants
Author/Authors :
Khajavi Rad, Abolfazl Neurogenic Inflammation Research Center - Department of Physiology - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Mohebbati, Reza Pharmacological Research Center of Medicinal Plants - Department of Physiology - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Hosseinian, Sara Pharmacological Research Center of Medicinal Plants - Department of Physiology - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran
Abstract :
Drug-induced nephrotoxicity is one of the most common causes of
acute kidney injury. There are various agents that exert nephrotoxic
effects through different pathogenic mechanisms. Aminoglycoside
antibiotics, chemotherapeutic agents, radiocontrast media,
and nonsteroidal anti-inflammatory drugs are among common
nephrotoxic agents. In recent years, natural compounds are being
increasingly used in the treatment of kidney diseases. Given many
reports available on the curative effects of a variety of medicinal
plants against drug-associated nephrotoxicity, we aimed to review
the protective effects of medicinal plants on certain nephrotoxic
drugs.
Keywords :
medicinal plants , cisplatin , gentamicin , nephrotoxicity , acute kidney injury
Journal title :
Iranian Journal of Kidney Diseases (IJKD)
