Title of article :
The efficacy of camel milk and Tarangabin (manna of Alhagi maurorum( combination therapy on glomerular filtration rate in patients with chronic kidney disease: A randomized controlled trial
Author/Authors :
Hosseini ، Mousa Alreza Department of Gastroenterology - School of Medicine - Mashhad University of Medical Sciences , Anushiravani ، Majid Department of Persian Medicine - School of Persian and Complementary Medicine - Mashhad University of Medical Sciences , Mojahedi ، Mohammad Javad Kidney Transplantation Complications Research Center, Ghaem Hospital, School of Medicine - Mashhad University of Medical Sciences , Hami ، Maryam Kidney Transplantation Complications Research Center, Ghaem Hospital, School of Medicine - Mashhad University of Medical Sciences , Zibaee ، Saeid Razi Vaccine and Serum Research Institute - Agricultural Research Education and Extension Organization (AREEO) , Rakhshandeh ، Hasan Pharmacological Research Center of Medicinal Plants - Mashhad University of Medical Sciences , Taghipour ، Ali Department of Epidemiology and Biostatistics - School of Health - Mashhad University of Medical Sciences , Nikakhtar ، Zahra Department of Persian Medicine - School of Persian and Complementary Medicine - Mashhad University of Medical Sciences , Eshraghi ، Hamid Kidney Transplantation Complications Research Center, Ghaem Hospital, School of Medicine - Mashhad University of Medical Sciences , Tavassoli ، Amir Parviz Department of Persian Medicine - School of Persian and Complementary Medicine - Mashhad University of Medical Sciences
Abstract :
Objective: This study was designed to investigate the effect of camel milk and Tarangabin (manna of Alhagi maurorum) combination therapy in addition to conventional treatments in patients with chronic kidney disease (CKD). Materials and Methods: Forty-four patients of 15 to 70 years old, with CKD due to hypertension or diabetes, and estimated glomerular filtration rate (eGFR) of 15–60 ml/min per 1.73 m2, were enrolled in this trial. The patients were randomized to receive either 400 cc of camel milk with 10 cc of Tarangabin syrup orally in two divided daily doses for 3 months plus conventional therapy or conventional therapy alone. The conventional treatment included diabetes medications and angiotensin converting enzyme inhibitors or angiotensin receptor blockers. Results: The baseline characteristics of patients were similar in the two groups. Serum levels of creatinine (p=0.01), blood levels of urea nitrogen (p=0.0001), triglyceride (p=0.02), and potassium (p=0.05), and diastolic blood pressure (p=0.0001) decreased, while eGFR (p=0.001) improved in intervention group significantly. Conclusion: It seems that the therapeutic protocol used in this study can improve renal function in patients with CKD through regulating glucose and anti-inflammatory, laxative, and immunostimulatory properties.
Keywords :
Camel milk , Tarangabin (Manna of Alhagi. maurorum) , Traditional Persian Medicine , Chronic kidney disease (CKD) , Glomerular filtration rate (GFR) , Randomized controlled trial
Journal title :
Avicenna Journal of Phytomedicine AJP)
Journal title :
Avicenna Journal of Phytomedicine AJP)
