Author/Authors :
Pourahmad, Aghdas Fertility, Infertility and Perinatology Research Center - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Saadati, Nasrin School of Medicine - Department of Social Medicine, Fertility, Infertility and Perinatology Research Center - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Barati, Mojgan Fertility, Infertility and Perinatology Research Center - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Moramezi, Farideh Fertility, Infertility and Perinatology Research Center - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Mohamadjafari, Razieh Fertility, Infertility and Perinatology Research Center - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Abstract :
Objectives: The study aimed to assess the frequency and type of abnormal karyotype in Khuzestan, Iran by amniocentesis before 22
weeks of gestation.
Methods:We conducted a retrospective analysis of 1197 amniotic fluid specimens in Khuzestan province, before 22 weeks gestations
for fetal karyotyping.
Results: The incidence of abnormal aneuploidies was 4.9% (59 of 1197) for all specimens. The highest chromosomal abnormality
was Down syndrome (64.4%).
Conclusions: The rate of chromosomal abnormalities was higher than other reports from Iran and all over the world. The detection
rate of Down syndrome similar to other reports remains high.
Keywords :
Chromosomal Abnormalities , Amniocentesis , Down Syndrome , Second Trimester
