Author/Authors :
ghorbel, i.b. department of internal medicine,la rabta hospital, Tunisia , feki, n.b. department of internal medicine,la rabta hospital, Tunisia , salem, t.b. department of internal medicine,la rabta hospital, Tunisia , hamzaoui, a. department of internal medicine,la rabta hospital, Tunisia , khanfir, m. department of internal medicine,la rabta hospital, Tunisia , lamloum, m. department of internal medicine,la rabta hospital, Tunisia , miled, m. department of internal medicine,la rabta hospital, Tunisia , houman, m.h. department of internal medicine,la rabta hospital, Tunisia
Abstract :
The association between microscopic polyangiitis (MPA) and primary biliary cirrhosis (PBC) has seldom been reported. We describe here a patient who presented with sensorimotor neuropathy along with hypothyroidism,renal failure and liver dysfunction. Detection of antinuclear antibodies at a titer of 1/800,anti-SSA,anti-SSB,anti-GP210,anti-microsomial and p-ANCA anti-myeloperoxydase antibodies along with renal,salivary and liver biopsy led to a diagnosis of MPA associated with PBC,Sjogren s syndrome and Hashimoto s thyroiditis.
