Study of non-compliance among chronic hemodialysis patients and its impact on patients outcomes

Non-adherence to prescription is common among hemodialysis (HD) patients and has been associated with significant morbidity. At least 50% of HD patients are believed to be non-adherent to some part of their treatment. We aimed to assess the prevalence of non-adherence to dialysis prescription among 100 chronic HD patients. We explored the relationship between non-adherence on one hand and socioeconomic profile,depression scores and cognitive function on the other hand. The impact of patients non-adherence on nutritional status,quality of life and dialysis adequacy was also assessed. The mean age of the study group was 50.51 ± 12.0 years. There were 62 females and 38 males in the study. Thirty-six patients (36%) were non-compliant to their dialysis prescription. No significant differences were detected between compliant and non-compliant patients in their education level and employment status. Inter-dialytic weight gain,serum phosphorus and depression scores were significantly higher in non-compliant patients compared with compliant patients,whereas body weight,serum albumin,serum calcium,quality of life scores and nutrition scores were significantly higher in compliant patients (P 0.05). In conclusion,non-adherence is highly prevalent among chronic HD patients and is associated with poor quality of life,depression and malnutrition.