Title of article
Loperamide Dependence: A Case Report
Author/Authors
Zarghami, Mehran Department of Psychiatry - School of Medicine and Psychiatry and Behavioral Sciences Research Center - Addiction Institute - Mazandaran University of Medical Sciences, Sari, Iran , Rezapour, Maryam Resident - Psychiatry and Behavioral Sciences Research Center - Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran
Pages
5
From page
59
To page
63
Abstract
Background: Loperamide is used as an antidiarrheal drug and is available over-the-counter. It cannot pass the blood-brain barrier and it does not have a considerable abuse potential. It can lead to dangerous cardiac arrhythmia.Case Report: Herein, we report a 35-year-old man with a 13-year history of abusing opioids who had undergone detoxification for four times during this period. He underwent detoxification for using 200 mg loperamide daily with anticholinergic agents, clonidine, non-steroidal analgesics, and diazepam. No evidence of arrhythmia was seen in the patient.Conclusion: Tolerating high doses of loperamide could be dangerous and increases the risk of fatal cardiac arrhythmias.
Keywords
Loperamide , Addiction , Cardiac arrhythmia
Journal title
Addiction and Health
Serial Year
2017
Record number
2522183
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