Dexmedetomidine: An All Sedation-in–One Drug in Critically Ill Patients with COVID-19

The coronavirus disease 19 (COVID-19) caused by SARSCoV-2 emerged as a public health threat in December 2019 and spread as a pandemic in March 2020. The virus can invade both respiratory and central nervous systems and can result in significant organ dysfunction. COVID-19 associated respiratory distress syndrome is an acute hypoxemic event which requires respiratory assistant. Hypoxemia itself and ventilation support (invasive or noninvasive) can induce agitation and require appropriate management. Direct invasion of virus to CNS can induce inflammation and delirium in these patients which requires accordance treatment.