Title of article :
Intravenous Immunoglobulin for Management of Non-paraneoplastic Autoimmune Retinopathy
Author/Authors :
Fekri, Sahba Ophthalmic Research Center - Shahid Beheshti University of Medical Sciences, Tehran - Department of Ophthalmology - Labbafinejad Medical Center - Shahid Beheshti University of Medical Sciences, Tehran , Soheilian, Masoud Ophthalmic Research Center - Shahid Beheshti University of Medical Sciences, Tehran - Department of Ophthalmology - Labbafinejad Medical Center - Shahid Beheshti University of Medical Sciences, Tehran , Rahimi-Ardabili, Babak Ophthalmic Research Center - Shahid Beheshti University of Medical Sciences, Tehran
Abstract :
Purpose: To report a case of non-paraneoplastic autoimmune retinopathy (npAIR) treated with intravenous immunoglobulin (IVIG).
Case report: A 12-year-old boy presented with progressive visual field loss, nyctalopia,
and flashing for three months. He had suffered from common cold two weeks before the
onset of these symptoms. On the basis of clinical history and paraclinical findings, he
was diagnosed with npAIR, and IVIG without immunosuppressive therapy was started.
During the one-year follow-up period after the first course of IVIG, flashing disappeared
completely. Visual acuity remained 10/10, but nyctalopia did not improve. Multimodal
imaging showed no disease progression.
Conclusion: Although established retinal degenerative changes seem irreversible in npAIR, IVIG may be a suitable choice to control the disease progression.
Keywords :
Autoimmune Retinopathy , Intravenous Immunoglobulin , Nyctalopia , Photopsia , Retinal Degeneration
Journal title :
Journal of Ophthalmic and Vision Research
