Title of article :
Green synthesis of isoquinoline derivatives using mlticomponent reaction of phthalaldehyde
Author/Authors :
Sharifi, Samanehsadat Department of Chemistry - Faculty of Sciences - University of Sistan and Baluchestan, sistan and Balouchestan, Iran , KohibT Maryam Department of Chemistry - Tarbiat Modares University, Tehran. Iran
Abstract :
Abstract: In this work, The 1,3-dipolar intermediates generated by addition of isoquinoline that is produced from the reaction of phthalaldehyde and ammonium acetate to dialkyl acetylenedicaboxylates are trapped by N-alkylisatins to produce spiro compounds in excellent yields.
Keywords :
Spiro compounds , N-Heterocycles. , Acetylenedicarboxylates
Journal title :
Iranian Journal of Organic Chemistry