Title of article
Efficient synthesis of imidazo oxazine using electron deficient acetylenic compounds
Author/Authors
Shams-Najafia, Jalal aDepartment of Chemistry - Faculty of Sciences - Ferdowsi University of Mashhad, Iran , Rostami-Charatib, Faramarz Research Center for Conservation of Culture Relicst (RCCCR) - Research institute of Cultural Heritage &Tourism, Tehran, Iran. , Sharific, Samaneh sadat Department of Chemistry - Faculty of Sciences - University of Sistan and Baluchestan - sistan and Balouchestan, Iran
Pages
4
From page
2921
To page
2924
Abstract
Abstract: An efficient synthesis of imidazo oxazins is described using a reaction of activated dialkyl acetylenedicarboxylates with acid chloride and ethanol in the Presence of imidazole. In addition, for existing imidazol and oxazin core in the synthesized compounds, evaluation of antioxidant activity was performed by radical trapping by DPPH and reducing power of ferric ion experiments. As a result, synthesized compounds show low radical trapping by DPPH and good reducing ability of ferric ion. The current procedure has the benefits for instance excellent yield of reaction, green media and easy separation of product.
Keywords
Dialkyl acetylenedicarboxylates. , Imidazole , Alkyl bromide , Activated acetylenic compounds
Journal title
Iranian Journal of Organic Chemistry
Serial Year
2020
Record number
2524146
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