2905 Biologically active compounds extracted from lindera oxyphylla

Abstract: The compounds [(2S)-5-hydroxy -6, 7-dimethoxy-2-phenyl chroman-4H-one] (1) 5, 7-dihydroxy -2(S)-phenyl chroman-4H-one (2),(E)-1-(2-hydroxy-4, 6-dimethoxyphenyl)-3-phenylprop-2-en-1-one (3), (E)-2-(1-hydroxy-3-phenylprop-2-en-1-ylidene)-4, 5-dimethoxy cyclopent-4-ene-1,3-dione( 4) and 2-cinnamoyl-3-hydroxy-4,5-dimethoxycyclopenta-2, 4-dienone (5).were obtained from phytochemical investigation of plant of Lindera Oxyphylla, a well medicinal plant. The structures of these compounds were established with the aid of spectroscopic methods, including analysis by 2D NMR spectroscopy. Determination of various antioxidant activities (2,2-diphenyl-1-picrylhydrazyl radical scavenging(DPPH), ferric reducing power(FRAP), ferrous ion chelating(FIC) of leaves and bark of Lindera Oxyphylla. Compounds1-5 significantly showed DPPH scavenging activity with IC50 values of 161.93 ± 0.004, 41.32 ± 0.005, 8.5 ± 0.004 , 157.58±0.002 and 149.45±0.01 ( , respectively, and FRAP with IC50% values of 467 ±0.02 ,273.93±0.005 ,167.74±0.02 ,469.48±0.03 and 429.33±0.03. FIC very low