Title of article :
Pan drug-resistant Acinetobacter baumannii causing nosocomial infections among burnt children
Author/Authors :
Sobouti, Behnam Burn Research Center - Iran University of Medical Sciences, Tehran, Iran , Mirshekar, Maryam Student Research Committee - Iran University of Medical Sciences, Tehran, Iran , Fallah, Shahrzad Shahid Beheshti University of Medical Sciences, Tehran, Iran , Tabaei, Aram Burn Research Center - Iran University of Medical Sciences, Tehran, Iran , Fallah Mehrabadi, Jalil The Lister Laboratory of Microbiology, Tehran, Iran , Darbandi, Atieh Student Research Committee - Iran University of Medical Sciences, Tehran, Iran
Abstract :
Background: Nosocomial infection caused by Acinetobacter baumannii has emerged as a world-wide serious problem in the
emergence of multidrug-resistant (MDR). Infections caused by antibiotic-resistant strains of A. baumannii cannot be completely
eliminated among the infected patients. This study aimed to monitor antibiotic resistance among A. baumannii strains isolated from burnt
children.
Methods: After performing biochemical identification tests on 115 isolates, 62 were detected as A. baumannii. Minimum inhibitory
concentration (MIC) was used to test susceptibility to colistin, and disk agar diffusion was used for the susceptibility of the isolates to
the antibiotics Ciprofloxacin, Amikacin, Gentamicin, Cefepime, Meropenem, Imipenem, Ceftazidime, Levofloxacin and
Piperacillin/Tazobactam. Bacterial species were isolated and identified as multidrug-resistant (MDR), extensively drug-resistant (XDR)
and pan drug-resistant (PDR), based on the susceptibility patterns to elected antibiotics, deputing different classes of antimicrobial.
Results: The antibiotic susceptibility pattern out of a total of 62 bacterial strains used in this study. Thirty-six (58%) strains were
categorized as MDR, 17 (27.5%) as XDR, and nine (14.5%) as PDR.
Conclusion: To reduce the threat of antimicrobial resistance, MDR, XDR and PDR A. baumannii strains must be evaluated by all
clinical microbiology laboratories.
Keywords :
PDR , Acinetobacter baumannii , Burnt Children
Journal title :
Medical Journal of the Islamic Republic of Iran