Histopathological and Clinical Characteristics of Secretory Carcinoma of the Breast

Secretory breast carcinoma is a rare form of invasive breast carcinoma constituting less than 1% of all breast cancer cases. Since insufficient data have been compiled about this rare tumor, it is important to report every case of secretory breast carcinoma in an effort to better understand the histopathological and clinical characteristics of this tumor and to contemplate the most appropriate therapeutic approach. In this report, two adult female patients over 50 years of age and a 14-year-old girl were reviewed with a detailed immunohistochemical work-up to define the clinical and molecular characteristics of secretory breast carcinoma.