Title of article :
Evaluation of hepatocellular carcinoma with computed tomography perfusion imaging
Author/Authors :
BAYRAKTUTAN, Ümmügülsüm Atatürk University - Faculty of Medicine - Department of Radiology, Turkey , KANTARCI, Abdulmecit Atatürk University - Faculty of Medicine - Department of Radiology, TURKEY , OĞUL, Hayri Atatürk University - Faculty of Medicine - Department of Radiology, Turkey , KIZRAK, Yeşim Atatürk University - Faculty of Medicine - Department of Radiology, Turkey , ÖZYİĞİT, Ömer Atatürk University - Faculty of Medicine - Department of Radiology, Turkey , YÜCELER, Zeyneb Atatürk University - Faculty of Medicine - Department of Radiology, Turkey , GENÇ, Berhan Şifa University - Faculty of Medicine - Department of Radiology, Turkey , ÖZOĞUL, Bünyami Ataturk University - Faculty of Medicine - Department of General Surgery, Turkey
Abstract :
Aim: To evaluate the role of computed tomography (CT) perfusion imaging in patients with hepatocellular carcinoma (HCC). Materials and methods: Seventeen patients (9 men, 8 women) with newly diagnosed HCC, proven by biopsy, were evaluated with 256-slice helical CT. Perfusion parameters of blood flow (BF), blood volume (BV), arterial perfusion (AP), portal perfusion (PP), and hepatic perfusion index (HPI) were calculated in the normal liver parenchyma and HCC samples. Results: A total of 21 histologically proven HCC lesions were evaluated from CT perfusion images. BF, BV, AP, and HPI values were shown to be significantly higher (P 0.05) in the HCC lesions than in the normal liver parenchyma. Conversely, PP values were found to be significantly lower (P 0.05) in HCC relative to liver parenchyma. Conclusion: CT perfusion imaging has the ability to evaluate tumor assessment, characterization, and neoangiogenesis in HCC.
Keywords :
Computed tomography , perfusion imaging , hepatocellular carcinoma
Journal title :
Turkish Journal of Medical Sciences (TJMS)
Journal title :
Turkish Journal of Medical Sciences (TJMS)
