Title of article :
Anti-Inflammatory and Anti-Nociceptive Effects of Ethanolic Extract of Mammea Africana Stembark In Rodents
Author/Authors :
Okokon, J. E. Univeristy Of Uyo - Department of Pharmacology Toxicology, Nigeria , Umoh, E.E Univeristy Of Uyo - Department of Pharmacology Toxicology, Nigeria , Umoh, U Univeristy Of Uyo - Department of Pharmacognosy and Traditional Medicine, Nigeria
Abstract :
The ethanolic stembark extract of M .africana (30-90 mg/kg) was investigated for pharmacological properties against egg white albumin - induced inflammation, Chemical as well as thermal- induced pain as well as yeast induced pyresis in rats. The extract demonstrated a dose – dependent anti- inflammatory , antinociceptive and antipyretic activities. These activities were comparable to that of ASA (100mg/kg). The stembark extract possess anti inflammatory , analgesic and antipyretic properties, which can be exploited in health care.
Keywords :
M. africana , anti inflammatory , analgesic , antipyretic
Journal title :
African Journal of Biomedical Research
Journal title :
African Journal of Biomedical Research
